NON-SMALL CELL LUNG CANCER (NSCLC), EGFR DOWNSTREAM PATHWAY ACTIVATION AND TKI TARGETED THERAPIES SENSITIVITY: EFFECT OF THE PLASMA MEMBRANE-ASSOCIATED NEU3.

Adenocarcinoma of Non-Small Cell Lung Cancer (NSCLC) is a severe disease.Patients carrying EGFR mutations may benefit from EGFR targeted therapies (e.g.: gefitinib).Recently, it has been shown that sialidase NEU3 directly interacts and regulates EGFR.In this work, we investigate the effect of sialidase NEU3 overexpression on EGFR pathways activatio

Yuyun Yueniwati,1 Ni Komang Darmiastini,1 Eko Arisetijono2 1Radiology Department, Faculty of Medicine, Brawijaya University, Malang, Indonesia; 2Neurology Department, Faculty of Medicine, Brawijaya University, Malang, Indonesia Background and objectives: Atherosclerosis causes reduction of the oxygen supply to structures in the far arterial wall, p

We propose Hunting Dogs that when individuals believe in fixed traits of personality (entity theorists), they are likely to expect a world of "uniformity." As such, they easily infer a population statistic from a small sample of data with confidence.In contrast, individuals who believe in malleable traits of personality (incremental theorists) are

The purpose of this study was to adapt the self-hate scale (SHS; Turnell et al., 2018) into Turkish in a community sample, and test the validity and reliability of the measure.The study was conducted with 234 individuals.After the translation procedures, the language equivalence was examined, and a significant positive relationship was found Huntin